sunI [2017-8-11 16:0:3]

bacteriocin producer immunity protein

locus: BSU21490

pI: 9.22

mw: 12.12 kDa

protein length: 105 aa

gene length: 315 bp

function: immunity to sublancin

product: bacteriocin producer immunity protein

essential: no

synonyms: yolF

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins]
• [category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.2|SP-beta prophage]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 2,269,988 → 2,270,305

Phenotypes of a mutant

• essential (facultative, ''[gene|5599DC922B2B70364603FB5566314D808D82DC08|sunI]'' can be deleted if ''[gene|1A6D90298D039FFFD977B2534952BA5E32B3530F|sunA]'' is also absent) [Pubmed|19047653], non-essential according to [Pubmed|28189581]

The protein

Catalyzed reaction/ biological activity

• mediates immunity to sublancin [Pubmed|19047653]

Protein family

• ribosomal protein S1P family (according to Swiss-Prot)

[SW|Localization]

• membrane anchored protein [Pubmed|19047653] [Pubmed|18763711]

Expression and Regulation

Operons

• genes: [gene|5599DC922B2B70364603FB5566314D808D82DC08|sunI]
  description: [Pubmed|22383849]

  additional information:

  • the expression is homogeneous in the population [pubmed|30808982]

Biological materials

Mutant

• GP1565 (''[gene|1A6D90298D039FFFD977B2534952BA5E32B3530F|sunA]-[gene|5599DC922B2B70364603FB5566314D808D82DC08|sunI]'', aphA3), available in [SW| Jörg Stülke]'s lab

Labs working on this gene/protein

• [SW|Jan Maarten van Dijl], Groningen, Netherlands

References

• 18763711,19047653,22383849,28189581